Deregulated metabolism is one of the hallmarks of cancer.It is well-known that tumour cells tend to metabolize glucose via glycolysis even when oxygen is available and mitochondrial respiration is functional.However, the lower energy efficiency of aerobic glycolysis with respect to mitochondrial respiration makes this behaviour, namely the Warburg
Abstract Background Habitat loss can force animals to relocate to new areas, where they would need home to adjust to an unfamiliar resource landscape and find new breeding sites.Relocation may be costly and could compromise reproduction.Methods Here, we explored how the Lesser black-backed gull (Larus fuscus), a colonial breeding seabird species wi
Objective To explore factors that potentially impact external validation performance while developing and validating a prognostic model for hospital admissions (HAs) in complex older general practice patients.Study design and setting Using individual participant data from four cluster-randomised trials conducted in the Netherlands and Germany, we u
This study examined the electrical and self-sensing capacities of ultra-high-performance fiber-reinforced concrete (UHPFRC) with and without carbon nanotubes (CNTs).For this, the effects of steel fiber content, orientation, and pore water content on the electrical and piezoresistive properties of UHPFRC without CNTs were read more first evaluated.T